Yuduo Guo / 郭钰铎

About Me

Building physics-informed AI that pushes the detection limits of real optical and astronomical instruments.

I am an Assistant Professor in the College of AI at Tsinghua University. I received my Ph.D. in Information and Communication Engineering from Tsinghua University in 2024, and was a Shuimu Scholar postdoctoral fellow in the Department of Automation before joining the College of AI.

My research advances Physics-informed AI for Science — a direction aimed at dissolving the boundary between physical hardware and computational intelligence. By embedding fundamental physical laws directly into neural network architectures, I pursue high fidelity and scientific trustworthiness even under extreme conditions. Conversely, by using AI models to guide and inspire hardware design, I aim to transcend detection limits imposed by classical physics. Together these establish a new paradigm for scientific discovery across optics, astronomy, and remote sensing.

I serve as a reviewer for Nature, IEEE TCSVT, Optica, and Optics Express, and as an Executive Editor for the special issue “Intelligent Optical Astronomical Observation Technology” in Laser & Optoelectronics Progress.

Physics-informed AI Computational Imaging Adaptive Optics AI for Astronomy Light Field Remote Sensing
Recruiting Ph.D. / M.S. students and interns

News

2026.08
Joined the College of AI, Tsinghua University as an Assistant Professor.
2026.07
Our Science paper received the Youth Outstanding Paper Award (Top 20) at the World Artificial Intelligence Conference (WAIC 2026); also named a Tsinghua University Outstanding Postdoctoral Fellow.
2026.07
Contributed talk at the European Astronomical Society Annual Meeting (EAS 2026) in Lausanne, Switzerland.
2026.06
Invited talks at the Institute of High Energy Physics, CAS and the National Astronomical Observatories, CAS on pushing detection limits with AI.
2026.05
Named a Qingyuan Scholar (清源学者) by the Chinese Association for Artificial Intelligence (CAAI).

Research

Physics-informed AI for Science

Embedding optical and physical priors into neural architectures so that learned models stay faithful and trustworthy under extreme, low-signal conditions.

Computational Optical Imaging

Meta-imaging sensors, light-field acquisition and digital adaptive optics — co-designing hardware and algorithms for aberration-corrected, gigapixel-scale imaging.

AI for Astronomy

Wide-field wavefront sensing, turbulence prediction and self-supervised denoising that extend the detection limits of ground- and space-based telescopes.

Selected Publications

Science 2026 Figure from the Science 2026 paper on astronomical denoising
Deeper detection limits in astronomical imaging using self-supervised spatiotemporal denoising
Yuduo Guo†, Hao Zhang†, Mingyu Li†, Fujiang Yu, Yunjing Wu, Yuhan Hao, Song Huang, Yongming Liang, Xiaojing Lin, Xinyang Li, Jiamin Wu*, Zheng Cai*, Qionghai Dai*
WAIC 2026 Youth Outstanding Paper — Top 20

We present ASTERIS, an astronomical self-supervised transformer-based denoising algorithm that integrates spatiotemporal information across multiple exposures. ASTERIS improves detection limits by 1.0 magnitude at 90% completeness and purity while preserving the point spread function and photometric accuracy. Applied to deep JWST images, it identifies three times more redshift ≳9 galaxy candidates, with rest-frame UV luminosity 1.0 magnitude fainter than previous methods.

Nat. Photonics 2024 Figure from the Nature Photonics 2024 paper on wide-field wavefront sensing
Direct observation of atmospheric turbulence with a video-rate wide-field wavefront sensor
Yuduo Guo†, Yuhan Hao†, Sen Wan†, Hao Zhang, Laiyu Zhu, Yi Zhang, Jiamin Wu*, Qionghai Dai*, Lu Fang*

We develop a light-field-based wide-field wavefront sensor (WWS) achieving direct observation of atmospheric turbulence over 1,100 arcsec at 30 Hz, with turbulence dynamics predicted 33 ms ahead. Described by MIT Prof. Dirk Englund as the state-of-the-art real-time wavefront sensing chip.

Nature 2022 Figure from the Nature 2022 paper on the meta-imaging sensor
An integrated imaging sensor for aberration-corrected 3D photography
Jiamin Wu†, Yuduo Guo†, Chao Deng†, Anke Zhang, Hui Qiao, Zhi Lu, Jiachen Xie, Lu Fang*, Qionghai Dai*
ESI Highly Cited Paper

We propose a meta-imaging sensor achieving gigapixel photography with a single spherical lens, enabling multisite aberration correction across 1,000 arcseconds on an 80-cm ground-based telescope. Recognized as one of China's Top 10 Optical Breakthroughs.

View all publications

Prospective Students

I am looking for self-motivated students to join me at the College of AI, Tsinghua University, to work on physics-informed AI, computational imaging, and AI for astronomy.

  • Ph.D. students — through Tsinghua's regular and direct-entry admission programs.
  • Master's students — both research and professional tracks.
  • Undergraduates & visiting interns — research projects, SRT, and thesis supervision.

Backgrounds in optics, computer vision, deep learning, astronomy, or signal processing are all welcome — what matters most is curiosity and persistence.

If you are interested, please email me with the subject line [Prospective Student] Your Name, attaching your CV and transcript:
gyd@tsinghua.edu.cn